2015 Annual Meeting
The 5th Annual Meeting of the American Society of Nanomedicine will be held on October 15-17, 2015.
The 2015 Conference Organizing Committee
Lajos P. Balogh
Howard E. Gendelman
5th Annual Meeting - Final Program
This year's ASNM annual meeting will highlight innovative applications of nanotechnology in both preclinical and clinical settings with special emphasis on translational nanomedicine. Workshops & educational sessions will offer guidance for scientists facing business, legal, and regulatory issues while translating their research findings into clinical applications. Ample opportunities will be provided for networking and interactions with leaders in the field and among the participants. Another highlight of the conference will be a session on nanomedicine's role in addressing the challenges of infectious diseases in global health.
In addition to the speakers listed below, posters will be submitted by graduate and post-doctoral trainees and those judged to be among the top four will receive awards on Saturday. Friday and Saturday, during an optional breakfast, “Meet-the-Expert” discussions will be held on a variety of topics geared to address questions and issues of young faculty, trainees, and anyone else. Friday noon a box lunch will be provided as part of the registration, and, participants may choose to attend an open audience Q&A session addressing business translational issues, which is followed by the Saturday AM session when speakers will talk about in more detail about these important topics.
To enhance inter-lab communication and networking, attendees are encouraged to provide a poster describing the research interests of the lab. These posters will be available for review throughout the meeting. They will also be projected in the meeting room before and during breaks as a continuous display changing about every 10 seconds or so to facilitate an appreciation for the research pursued in our different labs and to enhance interaction and collaboration.
2:00 Opening remarks: Esther H. Chang, Ph.D.
Chairman’s Opening Session Presentation
2:05 Theranostic Nanomedicine: “We’ve come a long way baby!”
Gregory M. Lanza, M.D. Ph.D., Professor of Medicine and Bioengineering, Oliver M. Langenberg Distinguished Professor of Science and the Practice of Medicine, Washington University Medical School
3:00 – 5:30 TOPIC: Nanomedicine Approaches to Vaccines and Anti-microbials
Moderator: James R. Baker, Jr. M.D
Keynote Speaker Presentation
3:00 Nanoparticle Vaccines; Shaping the Immune Response
Keynote Speaker - James R. Baker, Jr. M.D., Ruth Dow Doan Professor of Biologic Nanotechnology,
Professor Emeritus of Internal Medicine and Biomedical Engineering, University of Michigan
3:30 Cationic Lipid Nanoparticles as Efficient Delivery Systems for Vaccines and Immunomodulatory Molecules
Danilo Casimiro, Ph.D., Executive Director, Infectious Diseases and Vaccines, Merck Research
Laboratories, Merck & Co
4:15 Tolerogenic nanoparticles for the prevention of anti-drug antibodies and the treatment of autoimmune disease
Takashi Kei Kishimoto, Ph.D., Chief Scientific Officer, Selecta Biosciences, Inc.
4:40 Attacking Leishmania, a protozoan parasite ravaging 12 million patients in poverty, with nanotechnology
Gul Shahnaz, Ph.D., Department of Pharmacy, Faculty of Biological Sciences, Quaid-I-Azam University, Islamabad, Pakistan. Pakistan-US Science and Technology Cooperation Program and an UNESCO awardee
5:05 Long-acting cell targeted nanoformulated anti-retroviral therapy
Benson Edagwa, Ph.D., Assistant Professor, Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center
End of Session
5:30 - 7:00 Reception and Poster review (Cash Bar)
8:30 Meet-the-Expert Breakfast
Moderator: Esther H. Chang, Ph.D.
9:30 - 12:00 TOPIC: Next Generation Preclinical Nanomedicine
Moderator: Kuan Wang, Ph.D.
9:30 A CRISPR look at gene editing: using CRISPR/Cas9 technology to make genetically modified cell lines and model organisms.
Shondra M. Pruett-Miller, Ph.D., Director of the Genomic Engineering and iPSC Center at Washington University School of Medical, Saint Louis, MO
9:55 Interactions between tumor microenvironment factors and nanomedicines influence efficacy
William Zamboni, PharmD. Ph.D., Associate Professor, Division of Pharmacotherapy and Experimental
Therapeutics n the Eshelman School of Pharmacy and Molecular Therapeutics in the Lineberger
Comprehensive Cancer Center, University of North Carolina
10:20 Targeted image-guided therapy of pancreatic cancer with stroma breaking nanoparticles
Lily Yang, M.D. Ph.D., Professor of Surgery and Nancy Panoz Chair of Surgery in Cancer Research,
Department of Surgery, Emory University School of Medicine
10:45 – 11:00 Break
11:00 Treatment of glioblastoma using a nanochain particle system
Stathis Karathanasis, Ph.D., Assistant Professor of Biomedical Engineering and Radiology
Director of the Cancer Nanotechnology Lab, Department of Biomedical Engineering, Case Western Reserve University
11:25 Breaking the depth dependency of phototherapy with Cerenkov radiation and low-radianceresponsive nanophotosensitizers
Samuel Achilefu, Ph.D., Director of Optical Radiology Lab, Professor of Radiology, Biochemistry &
Molecular Biophysics and Biomedical Engineering, Department of Radiology, Washington University School of Medicine
11:50 Addressing the need for nanomedicines targeting hydrophobic compounds
Gert Storm, Ph.D., Professor of targeted drug delivery at the University of Utrecht and Professor of targeted therapeutics at the MIRA institute of the University of Twente.
12:15 – 1:30 Box Lunch
12:20 – 1:10 Nanomedicine Translational Issues – Panel discuss audience Q&A
Moderator: Raj Bawa, Ph.D.
Friday Afternoon Session
1:30 – 5:00 TOPIC: Clinical Translation of Nanomedicines
Moderator: Michelle S. Bradbury, M.D. Ph.D.
Keynote and Lifetime Achievement Award to Ruth Duncan, Ph.D.
1:35 Effective Translation of Innovative Medicinal Products: Understanding the Landscape, Asking the Right Questions, and Use of Robust Scientific Methodology
Ruth Duncan, Ph.D., Professor Emerita, prior Director of the Centre for Polymer Therapeutics at the
Welsh School of Pharmacy, Cardiff University, UK
2:10 NCI Alliance for Nanotechnology in Cancer - a Model for Stimulating Transitions from Academic Research to Clinical Applications
Piotr Grodzinski, Ph.D., Director NCI Office of Cancer Nanotechnology Research, National Institute of Health
2:35 The NanoTherm Therapy – Fighting Cancer with Nanotechnology
Hoda Tawfik, M.D. Ph.D., Chief Medical Officer and Chief Operating Officer for Therapy Development,
3:00 Development of liposome-based cancer nanomedicines - DOXIL and beyond
Alberto A. Gabizon, M.D. Ph.D., Director, Oncology Institute, Shaare Zedek Medical Center, and
Professor of Oncology, The Hebrew University of Jerusalem; President and Founder, LipoMedix Pharmaceuticals.
3:25 – 3:45 Break
3:45 New Developments in Targeted Gold Nanomedicines
Steven K. Libutti, M.D., Professor and Vice Chair, Department of Surgery, Associate Director for Clinical Services of the Albert Einstein Cancer Center, Albert Einstein College of Medicine
4:10 Translation of an effective cancer nanomedicine: is a targeting moiety truly necessary?
Esther H. Chang, Ph.D., Professor, Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center ND and Founder of SynerGene
4:35 Ultrasmall Dual-Modality C dots as Image-Guided Therapeutic Platforms for Oncology
Michelle S. Bradbury, M.D. Ph.D., Director, Intraoperative Imaging, Member, Molecular Pharmacology and Chemistry Program, and Associate Professor of Radiology, Weill Cornell Medical College and Memorial Sloan Kettering Cancer Center
End of Session
5:00 – 6:00 Moderated Posters: Howard E. Gendelman, M.D.
8:30 Meet-the-Expert Breakfast
Moderator: Esther Chang, Ph.D.
9:30 – 11:40 TOPIC: Enabling the Business side of translation
Moderator: Raj Bawa, Ph.D.
9:30 Overview (IP, FDA, regulatory, critical current related issues)
Raj Bawa, Ph.D., Patent Agent, Bawa Biotech LLC (Ashburn, VA)
Adjunct Professor of Biological Sciences, Rensselaer Polytechnic Institute (Troy, NY)
9:50 Translational Pipeline to the Clinic – Navigating Key Challenges and Regulatory Guidances
Michelle S. Bradbury, M.D. Ph.D., Associate Member, Memorial Sloan Kettering Cancer Center (New York, NY) Associate Professor of Radiology, Weill Medical College of Cornell University (New York, NY),
and Ulrich Wiesner, Ph.D., Spencer T. Olin Professor of Engineering, Department of Materials, Science
& Engineering, Cornell University (Ithaca, NY), Co-founders, Claymore Technologies
10:15 Patent Issues for an Academic Inventor – What, Why and How?
Brian Reese, Ph.D. J.D. M.B.A., Associate, Choate, Hall & Stewart LLP (Boston, MA)
10:40 Roadmap to the Clinic – What, Why and How in Nanotox Assessment?
János Szebeni, M.D. Ph.D. D.Sc. Professor of Nanobiotechnology, Miskolc University (Budapest,
Hungary); Professor and Head, Nanomedicine Research and Education Center Semmelweis University School of Medicine (Budapest, Hungary)
11:05 Investigational New Drug (IND) Applications – What, Why and How?
William Haulbrook, Ph.D. J.D. Partner, Choate, Hall & Stewart, LLP (Boston, MA)
11:25 Licensing Medical Intellectual Property – What, Why and How?
Annette I. Kahler, J.D., Senior Counsel, Heslin Rothenberg Farley & Mesiti PC (Albany, NY)
End of Session
11:45 - 1:00 Best Poster Awards and Presentations
Moderator: Lajos P. Balogh, Ph.D.
1:00 Closing remarks: Esther H. Chang, Ph.D.
Abstract Submission - Note the New Deadline:
The new deadline for the poster abstracts is October 5th, 2015.
ASNM Poster Competition - 2015
The winners of the top four posters submitted by young (pre- and post-doctoral) investigators will be selected to give a short ten minute (8 slides) oral presentation on Saturday October 17, 2015 at the conference.